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PicoTip® in Action
Stability at low-flow rates! Think of what this could do for your
nano-HPLC/MS.
This kind of performance is difficult to achieve with cleaved,
flat-ended silica tips.
These images are frame captures of a PicoTip® spraying 5% Acetic acid in
30% MeOH at 200 nl/min by direct infusion from a syringe pump. Each
frame differs by an applied voltage of approximately 100 volts. The
tip-to-inlet distance was ca. 5 mm.
900 V - no spray
1000 V - Taylor-cone/droplet oscillation, more "drops" than spray
1100 V - cone/droplet oscillation. approx 50% spray
1200 V - cone/droplet oscillation, on the verge of a stable Taylor cone
1300 V - stable cone-jet
1400 V - cone-jet on the verge of "jumping", slight instability
1550 V - multiple cone-jets
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