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Events | Presentations & Posters

Posters Presented at ASMS 2007 - Indianapolis, Indiana

(Files require Adobe Acrobat Reader)
Correlating Extended Dynamic Range with Nanospray Flow Rate Measurement for Optimal ESI-MS Performance
Carla J. Marshall-Waggett, Christopher J. Toher, Gary A. Valaskovic
New Objective, Woburn, MA
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Inline Electrospray Current Conductivity Detection for Characterization of Mobile Phase Composition and Gradient Delay
Adam W. Perala, Gary A. Valaskovic
New Objective Inc, Woburn, MA
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Efficient Column-to-Column Coupling with Multiple Columns for Enhanced nLC-ESI-MS Separation
Christopher Toher, Adam W. Perala, Carla J. Marshall-Waggett, Gary A. Valaskovic
New Objective Inc, Woburn, MA
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A Novel Fused-core Silica Particle Based Nanobore Column for Ultra-high Performance Nanoelectrospray Mass Spectrometry
Robert Moody1; Gary A. Valaskovic2; Mike S. Lee3
1MAC-MOD Analytical, Chadds Ford, Pennsylvania, 2New Objective, Inc., Woburn, MA, 3Milestone Development Services, Newtown, PA
Not available for download

Ultra-Performance Peptide Analysis via Nanobore LC-ESI-MS with Sub-2µm Particles
John M. Neveu1, William S. Lane1, Gary A. Valaskovic2 1Harvard University, Cambridge, MA;
2New Objective, Inc., Woburn, MA
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Digitized Nanobore LC-MS: An Automated Control System with Emitter Divert for Column-Switching
Mike S. Leesup>1, Gary A. Valaskovic2 1Milestone Development Services, Newtown, PA, 2New Objective, Inc., Woburn, MA
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Evaluation of Fluoropolymer Frit Performance in High-pH Nano-ESI Applications
Jeffrey Wynn, Adam W. Perala, Christopher J. Toher, Gary A. Valaskovic
New Objective Inc, Woburn, MA
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On-line 1D and 2D nanoLC-ESI-MS using 10-µm-i.d. Porous Layer Open Tubular Polystyrene-divinylbenzene Columns for Ultrasensitive Proteomic Analysis
Quanzhou Luo1, Guihua Yue1, Gary A. Valaskovic2, Ye Gu1, Dongdong Wang1, Shiaw-Lin Wu1, Barry L. Karger1
1The Barnett Institute, Northeastern University, Boston, MA, 2New Objective, Inc., Woburn, MA
Not available for download

Posters Presented at ABRF 2007 - Tampa, Florida

(Files require Adobe Acrobat Reader)
Inline Electrospray Current Conductivity Detection for Characterizing Mobile Phase Composition and Gradient Delay
Gary A. Valaskovic, Adam W. Perala, Christopher J. Toher
New Objective Inc, Woburn, MA
Size: 684 K | Download Poster

Long- & Mixed-Column Nanobore Chromatography for Complex Proteomic Analysis
Christopher J. Toher, Adam W. Perala, Carla J. Marshall-Waggett, Gary A. Valaskovic
New Objective Inc, Woburn, MA
Size: 936 K | Download Poster

Examination of Nanobore Capillary Trapping Column Geometries for Analysis of Peptide Mixtures
John M. Neveu1, Christopher J. Toher2, William S. Lane1, Gary A. Valaskovic2
1Harvard University, Cambridge, MA   2New Objective Inc, Woburn, MA
Size: 968 K | Download Poster

Rapid Nanobore LC-ESI-MS Peptide Analysis Using Sub-3 µm-Diameter Resins
Adam W. Perala, Christopher J. Toher, Carla J. Marshall-Waggett, Gary A. Valaskovic
New Objective Inc, Woburn, MA
Size: 516 K | Download Poster

Posters Presented at ASMS 2006 - Seattle, Washington

(Files require Adobe Acrobat Reader)
Optimization of Nanobore Capillary Trapping Column Geometries for Analysis of Peptide Mixtures
John M. Neveu1, Christopher J. Toher2, William S. Lane1, Gary A. Valaskovic2
1Harvard University, Cambridge, MA   2New Objective Inc, Woburn, MA
Size: 1.2 MB | Download Poster

High-Pressure, Transparent Microfluidic Coupling Method for Nanobore LC-MS
Jeffrey J. Wynn, Christopher J. Toher, Adam W. Perala, Gary A. Valaskovic
New Objective Inc, Woburn, MA
Size: 536 K | Download Poster

Digitized Nanobore LC-MS Control System with Integrated Emitter Divert & Rinse for Improved Nanospray Performance
James L. Stephenson1, Jonathan L. Bundy1, Gary A. Valaskovic2, Mike S. Lee3
1RTI International, Research Triangle Park, NC   2New Objective Inc, Woburn, MA   3Milestone Development Service, Inc., Newtown, PA
Size: 552 K | Download Poster

Offline Nano-ESI Phosphopeptide Analysis with TiO2, and ZrO2 Wall-Coated Trap'nTips™
Christopher J. Toher1, Adam W. Perala1, Ashok K. Shukla2, Gary A. Valaskovic1
1New Objective Inc, Woburn, MA   2Glygen, Inc., Columbia, MD
Size: 332 K | Download Poster

Posters Presented at ABRF 2006 - Long Beach, California

(Files require Adobe Acrobat Reader)
Offline Nano-ESI Phosphopeptide Analysis with Carbon, TiO2, and ZrO2
Wall-Coated Trap'nTips™

Christopher J. Toher1, Adam W. Perala1, Ashok K. Shukla2, Gary A. Valaskovic1
1New Objective Inc, Woburn, MA  2Glygen, Inc., Columbia, MD
Size: 272 K | Download Poster

PicoClear™ Union Technology Applications for Nano ESI-MS Molecules
Carla J. Marshall-Waggett, Adam W. Perala, Christopher J. Toher, Gary A. Valaskovic
New Objective Inc, Woburn, MA
Size: 460 K | Download Poster

Evaluation of Fluoropolymer Frit Performance in High-pH Nano-ESI Applications
Adam W. Perala, Christopher J. Toher, Gary A. Valaskovic
New Objective Inc, Woburn, MA
Size: 480 K | Download Poster

Posters Presented at ASMS 2005 - San Antonio, Texas

(Files require Adobe Acrobat Reader)
Automated Orthogonal ESI Control System with Optimized Plume-Inlet Positioning
Mike S. Lee 1, Gary A. Valaskovic2
1Milestone Development Services, Inc.  2New Objective Inc, Woburn, MA
Size: 432 K | Download Poster

Sample Purification for Static Nanospray MS Using Wall-Coated Pipette Trap'nTips™
Christopher J. Toher 1, Adam W. Perala 1, Ashok K. Shukla 2, Gary A. Valaskovic1
1New Objective Inc, Woburn, MA  2Glygen, Inc., Columbia, MD
Size: 636 K | Download Poster

Enhanced Nanobore LC-MS Using Methanol Gradient Elution with Peptide Mixtures
Adam W. Perala, Christopher J. Toher, Gary A. Valaskovic
New Objective, Inc., Woburn, MA
Size: 756 K | Download Poster

TIC-Mediated Flow Rate Variation for Flow-Injection Nanospray Analysis
Carla J. Waggett1, David Neyer2, Adam W. Perala1, Christopher J. Toher1, Gary A. Valaskovic1
2New Objective, Inc., Woburn, MA  2Eksigent Technologies, Livermore, CA
Size: 328 K | Download Poster

Charged Droplet Solvent Extraction from Surfaces: Desoprtion Electrospray Ionization of Small Drug Molecules (Abstract only)
Gary A. Valaskovic1, Mike S. Lee2
1New Objective Inc, Woburn, MA  2Milestone Development Services, Inc.
Size: 150 K | Download Abstract

Posters Presented at ASMS 2004 - Nashville, TN

(Files may require Adobe Acrobat Reader)
Method to Optimize Sensitivity and Throughput on a Hybrid Quadrupole-TOF Instrument for LC/MS-Based Peptide and Proteomic Analysis
Joseph Bonapace1, Jennifer Rutherford1, James P. Murphy III2, Gary A. Valaskovic2
1Charles River Proteomic Services, Worcester, MA 2New Objective Inc, Woburn, MA
Size: 500 K | Download Poster

Automated Orthogonal Control System for Electrospray Ionization Mass Spectrometry
Gary A. Valaskovic1, James P. Murphy III1, Mike S. Lee2
1New Objective Inc, Woburn, MA 2Milestone Development Services, Newtown, PA
Size: 664 K | Download Poster

Minimizing Post-Column Band Broadening in Nanobore LC-MS/MS for Bottom-up Proteomic Applications
Andreas Huhmer1, James P. Murphy III2, Gary A. Valaskovic2
1Thermo Electron Corp., San Jose, CA 2New Objective, Inc., Woburn, MA
Size: 744 K | Download Poster

Fundamental Studies on the Application of Nanobore LC-MS for the Analysis of Small Drug Molecules
Mike S. Lee1, James P. Murphy III2, Gary A. Valaskovic2
1Milestone Development Services, Newtown, PA 2New Objective, Inc., Woburn, MA
Size: 492 K | Download Poster

Automated ESI Control on Variable-Flow Gradient Nanobore LC-MS
James P. Murphy III1, Gary A. Valaskovic1, Karen M. Hahnenberger2, David W. Neyer2
1New Objective Inc, Woburn, MA 2Eksigent Technologies, Livermore, CA
Size: 700 K | Download Poster

Posters Presented at ASMS 2003 - Montreal, Quebec, Canada

Fabrication and Use of 20 µm ID Nanobore Columns
Gary A. Valaskovic and James P. Murphy III
New Objective, Inc., Woburn, MA
Abstract only available
Size: 144 K| Download Abstract
Trap/Column Combination to Optimize Sensitivity and Sequence Coverage
James P. Murphy III and Gary A. Valaskovic
New Objective, Inc., Woburn, MA
Size: 764 K| Download Poster
Variable Flow Gradient LC-MS: Spray Mode Signal Affects and Control
Mike S. Lee, Gary A. Valaskovic, and James P. Murphy III
New Objective, Inc., Woburn, MA
Size: 1.4 MB| Download Poster

Poster Presented at ABRF 2003

A Comprehensive Study on Nanobore Injection Methods for Proteomics
James P. Murphy III and Gary A. Valaskovic
New Objective, Inc., Woburn, MA
Size: 2 MB | Download Poster

Industrial Seminar Presented at HPCE 2003

Practical High Sensitivity LC-MS: Fundamentals, Challenges, and Prospects
Gary A. Valaskovic
New Objective, Inc, Woburn, MA
Size: 5.8 MB | Download PPT Presentation

Technical Abstracts from ASMS 2002

Improved Nanospray Emitter Coatings for Nanospray LC-MS
James P. Murphy III and Gary A. Valaskovic
New Objective, Inc, Woburn, MA
Size: 76 K | Download Abstract

Taylor Cone Stability and ESI Performance for LC-MS at Low Flow Rates
1Mike S. Lee, 2James P. Murphy III, 2Gary A. Valaskovic
1Milestone Development Services, Newtown, PA 2New Objective Inc, Woburn, MA
Size: 1.2 MB | Download Abstract

Orthogonal Control Systems for ESI-MS and Nanobore LC-MS
1Gary A. Valaskovic, 1James P. Murphy III, 2Mike S. Lee
1New Objective Inc, Woburn, MA 2Milestone Development Services, Newtown, PA
Size: 188 K | Download Abstract



Events | Presentations & Posters