Press Releases

New Objective is awarded U.S. Patent on automated orthogonal control system for electrospray ionization mass spectrometry
August 2004 - U.S. Patent 6,744,046 was issued to Gary Valaskovic and Mike S. Lee for an automated orthogonal control system for electrospray. The new system enables optimal spray controlled automatically via computerized feedback versus operator control as has been the traditional format for electrospray and nanospray delivery.

Since the late 1980s, electrospray ionization mass spectrometry (ESI-MS) has become an integral tool in the life sciences. ESI/MS-based methods are now routinely applied throughout drug discovery and development impacting both small molecule and large molecule applications, such as proteomics. Founded by Gary Valaskovic in 1997 on PicoTip^® technology, a revolutionary line of emitters for LC-MS, New Objective has remained on the cutting edge of nanobore chromatography and nanospray-based mass-spectrometry through close communication with its customers, continuous innovation, and dedication to quality. Valaskovic is the holder of 6 other U.S. Patents.

"This patent affirms New Objective's leadership in ultra high-sensitivity LC-MS," states Valaskovic. "This important technology enables delivery of truly optimized performance in an automated environment to an ever-widening market."

Currently, New Objective plans to offer licensing opportunities and seek out collaborative partners to further technology development. Plans are in place to incorporate first generation technology into New Objective's highly-regarded line of PicoView^® nanospray sources.

Download full press release PicoView^® 550 for Thermo LTQ™ and LTQ FT™ Released
May, 2003 - New Objective, Inc., the industry leader in nanospray technology for mass spectrometry, introduces the latest addition to their PicoView^® line of nanospray sources for high-sensitivity mass spectrometry, the PicoView 550 Series for Thermo's newest mass spectrometers the LTQ^® and LTQ FT™.

The PicoView 500 Series represents a leap forward in user design with a magnetic interlock stage system. This unique design allows modification and changes to the emitter and column outside of the source housing. No tools or screws required, the magnetic plate simply snaps back into exact position with no further optimization necessary. An improved imaging system provides clear imaging of the spray for assured, quick tuning. As with the other models, the PicoView for the LCQ Deca XP/XP Plus comes equipped with a translation stage, universal microinjection valve mount, mounting hardware and fittings for interfacing nanobore LC-MS. An assortment of PicoTip™ emitters, including a PicoFrit^® column, is included with the PicoView system.

See the PicoView^® product line for further information, or contact us at sales@newobjective.com. PicoView^® 500 for Thermo LCQ Deca XP/XP Plus™ Released
May, 2003 - New Objective, Inc., the industry leader in nanospray technology for mass spectrometry, introduces the latest addition to their PicoView^® line of nanospray sources for high-sensitivity mass spectrometry, the PicoView 500 Series for LCQ Deca XP and XP Plus™ from Thermo Finnigan.

The PicoView 500 Series represents a leap forward in user design with a magnetic interlock stage system. This unique design allows modification and changes to the emitter and column outside of the source housing. No tools or screws required, the magnetic plate simply snaps back into exact position with no further optimization necessary. An improved imaging system provides clear imaging of the spray for assured, quick tuning. As with the other models, the PicoView for the LCQ Deca XP/XP Plus comes equipped with a translation stage, universal microinjection valve mount, mounting hardware and fittings for interfacing nanobore LC-MS. An assortment of PicoTip™ emitters, including a PicoFrit^® column, is included with the PicoView system.

See the PicoView^™ 500 product for further information, or contact us at sales@newobjective.com. New Patent for New Objective
August 2002 - New Objective, Inc. has been awarded U.S. Patent number 6,395,183, for the development of multi-stage packing methods that are now used in the production of PicoFrit^® and IntegraFrit™ columns. This novel approach to nanobore column fabrication ensures a high quality, economical product. The R & D effort that led to this development is part of New Objective's commitment to product innovation in LC-MS. New Coating Now in Use
May 2002 - A novel Platinum/SiO multilayered coating, (U.S. Patent 5,788,166) is now in use for online SilicaTip™ emitters. This new coating has excellent adhesion properties with fused silica and is capable of operating even after multiple electrical discharges. SilicaTip emitters are able to perform electrospray for hundreds of hours of continuous operation (over 800 hours with a MeOH/Water/Acetic Acid mobile phase) without a loss of coating. All SilicaTips, with our standard coating, are being shipped with this new coating, designated by -CE- in the stock number. There is no additional expense to the consumer for the improved coating.

For more information on the new coating download the technical abstract from the ASMS 2002 poster presentation New Chemistries for Sample Trap
April 2002 - New Objective offers new chemistries and sizes for the Upchurch Scientific® capillary sample trap. IntegraFrit™ trap inserts are nanobore columns that load into the trap cartridge assembly. The selection of available packing materials is optimized for proteomics and can be used in injection loops for sample prep, as nanobore guard columns or for rapid sample analysis. The IntegraFrit trap insert is a 2.5 cm fused-silica column with an outer diameter of 360 µm and inner diameter of either 75 or 100 µm. The ultra-low volume, (less than 2 nL), IntegraFrit is internal to the column, and reduces tailing caused by extra-column frits. For more information, including available sizes and chemistries, visit the IntegraFrit Trap Insert section, or email us at sales@newobjective.com. Upchurch Scientific is a registered trademark of Upchurch Scientific. Biphasic PicoFrit^® Columns Available
April 2002 - Biphasic PicoFrit^® columns now commercially available. By combining high-quality strong cation exchange material with ProteoPep™ C18 for peptide analysis, researches can now analyze complex protein digests in a single run. Adapting the robust PicoFrit format to shotgun digests (Washburn, M.P., D. Wolters and J.R. Yates, Nature Biotechnology 19, (2001):242:247.) complex mixture analysis can now be routine. PicoFrit columns combine emitter and column to eliminate post-column losses and reduce tip clogging while providing high-resolution separations. Prepacked IntegraFrit™ Columns Available
January 2002 - Prepacked IntegraFrit™ columns for high-sensitivity nanobore LC now available in a selection of sizes and packing materials. IntegraFrit columns have an internal frit, which virtually eliminates tailing caused by extra-column frits. Adding very little back-pressure, the internal frit is free of adhesives, binders and polymers and is compatible with ESI-MS, MALDI and biomolecule analysis. Available packed with ProteoPep™ for peptide analysis or high-performance strong cation exchange material. Short IntegraFrit columns are effective for sample trapping and desalting procedures while longer columns are designed for nanobore LC. New Objective can custom pack user-supplied materials. PicoView^® 400 Series for ABI QSTAR™
October 2001 - A new PicoView^® system has been introduced for Applied Biosystems QSTAR™ series mass spectrometer. The latest model of PicoView utilizes a kinematic stage plate to make accessing the experimental set-up easier by enabling rapid column or emitter replacement. Building on the tradition of innovation and functionality, the latest PicoView includes the same modular design and flexibility of experimental set-up as the PicoView models for Thermo Finnigan, Micromass, Bruker and Agilent instruments. As with the other models, the PicoView for ABI comes equipped with a high-resolution imaging system, translation stage, microinjection valve, mounting hardware and fittings for interfacing nanobore LC-MS. An assortment of PicoTip™ emitters, including a PicoFrit^® column, is included with the PicoView system. QSTAR is a trademark of Applera Corporation or its subsidiaries in the U.S. and certain other countries. Stock #PV-400-Q New Probe Modification Kit Introduced
August 2001 - New Objective, Inc has introduced the PFZ-ADP probe modification kit to enable the use of industry-standard PicoFrit^® columns with existing Micormass Z SPRAY™ NanoFlow™ stage. PicoFrit columns avoid problems associated with connecting columns to ESI tips while assuring optimal chromatographic performance. The kit contains everything needed for success in the first experience with PicoFrit nanobore LC columns. Read Technical Note PF-3 to learn more about the PFZ-ADP kit and its quick installation. New Patent for New Objective, Inc.
August 2001 - New Objective, Inc. announces it has recently received U.S. Patent number 6,190,559, in addition to its earlier U.S. Patent 5,997,746, for the development of evaporative packing methods in the production of PicoFrit^® columns. This important technology affirms New Objective's commitment to developing and bringing to market the highest quality tools for ultimate sensitivity LC-MS. PicoView^® 300 Series for Micromass Z SPRAY™
June 2001 - Complete PicoView^® system for Micromass Q-ToF™ or LCT™ including high resolution imaging system with video and direct viewing, translation stage, micro injection valve and mounting hardware. Also includes an assortment of PicoTips™, including a PicoFrit^® column with proper fittings for interfacing nanobore LC-MS and continuous flow nanospray. All you need to add is your sample! Stock #PV-300-Q for Q-ToF™ Stock #PV-300-L for LCT™ PicoView^® 200 Series for Bruker Esquire™ and Agilent LC/MSD-Trap
June 2001 - PicoView^® system as above, configured for Bruker Daltonics Esquire™ 2000 and 3000 mass spectrometers and Agilent LC/MSD-Trap. Also includes hardware for static nanospray. Stock #PV-200-E for Bruker Esquire™ Stock #PV-200-A for Agilent LC/MSD-Trap New PicoView^® system for Applied Biosystems QSTAR™ series. A kinematic stage plate enables rapid column or emitter replacement by easy access to experimental set-up.